Publication 2020-2021

Previous Publications

2020-2021 Publications  


  1. Haslam DE, Li J, Liang L, Martinez M, Palacios C, Trak-Fellermeier MA, Franks PW, Joshipura K, Bhupathiraju SN. Changes in Metabolites During an Oral Glucose Tolerance Test in Early and Mid-Pregnancy: Findings from the PEARLS Randomized, Controlled Lifestyle Trial. Metabolites. 2020 Jul 10;10(7). doi: 10.3390/metabo10070284. PubMed PMID: 32664282.

  2. Hernandez-Suarez DF, Melin K, Marin-Maldonado F, Nunez HJ, Gonzalez AF, Gonzalez-Sepulveda L, Rivas-Tumanyan S, Naik H, Ruaño G, Scott SA, Duconge J. Implementing a pharmacogenetic-driven algorithm to guide dual antiplatelet therapy (DAPT) in Caribbean Hispanics: protocol for a non-randomised clinical trial. BMJ Open. 2020 Aug 6;10(8):e038936. doi: 10.1136/bmjopen-2020-038936. PubMed PMID: 32764090.

  3. Reyes-González S, de Las Barreras C, Reynaldo G, Rodríguez-Vera L, Vlaar C, Mejias VL, Monbaliu JM, Stelzer T, Mangas V, Duconge J. Genotype-driven pharmacokinetic simulations of warfarin levels in Puerto Ricans. Drug Metab Pers Ther. 2020 Aug 19;. doi: 10.1515/dmdi-2020-0135. [Epub ahead of print] PubMed PMID: 32809952; NIHMSID:NIHMS1622426.

  4. Melendez L, PhD, Zenon-Melendez C, Ms, Lima AR, Carrasquillo-Carrión N K, Ms, Cantres-Rosario Y, Bs. Cathepsin B/ SAPC inhibition deregulates apoptosis-related proteins in neuronal cells exposed to supernatants from HIV-infected macrophages. J Biomol Tech. 2020 Aug;31(Suppl):S19. PubMed PMID: 32831716; PubMed Central PMCID: PMC7424844.

  5. El Rouby N, Marcatto LR, Claudio K, Tavares LC, Steiner H, Botton MR, Lubitz SA, Fallon EN, Yee K, Kaye J, Scott SA, Karnes J, Santos PCJL, Duconge J, Cavallari LH. Multi-site investigation of genetic determinants of warfarin dose variability in Latinos. Clin Transl Sci. 2020 Aug 29;. doi: 10.1111/cts.12854. [Epub ahead of print] PubMed PMID: 32860733.

  6. Rodríguez-Escudero I, Cedeño JA, Rodríguez-Nazario I, Reynaldo-Fernández G, Rodríguez-Vera L, Morales N, Jiménez-Vélez B, Ruaño G, Duconge J. Assessment of the clinical utility of pharmacogenetic guidance in a comprehensive medication management service. J Am Coll Clin Pharm. 2020 Sep;3(6):1028-1037. doi: 10.1002/jac5.1250. Epub 2020 May 2. PubMed PMID: 32964197; PubMed Central PMCID: PMC7505210.

  7. Reig-López, J., Maldonado, M., Merino-Sanjuan, M., Cruz-Collazo, A. M., Ruiz-Calderón, J. F., Mangas-Sanjuán, V., Dharmawardhane, S., & Duconge, J. (2020). Physiologically-Based Pharmacokinetic/Pharmacodynamic Model of MBQ-167 to Predict Tumor Growth Inhibition in Mice. Pharmaceutics, 12(10), 975.

  8. Güette Fernández, J. R., Pita, X. N., Meléndez, E., & Parés Matos, E. I. (2020). Interaction of metallocene dichlorides with apo-human transferrin: A spectroscopic study and cytotoxic activity against human cancer cell lines. International journal of molecular biology (Edmond, Okla.), 5(3), 79-109.

  9. Hampel, S., Eichler, K., Yamada, D., Bock, D. D., Kamikouchi, A., & Seeds, A. M. (2020). Distinct subpopulations of mechanosensory chordotonal organ neurons elicit grooming of the fruit fly antennae. eLife, 9, e59976.

  10. Maldonado-Hernández, R., Quesada, O., & Lasalde-Dominicci, J. A. (2020). Biophysical characterization dataset of native nicotinic acetylcholine receptor in lipid-like detergent complexes. Data in brief, 32, 106230.

  11. Heredia, F. L., Resto, P. J., & Parés-Matos, E. I. (2020). Fast Adhesion of Gold Nanoparticles (AuNPs) to a Surface Using Starch Hydrogels for Characterization of Biomolecules in Biosensor Applications. Biosensors, 10(8), 99.

  12. Lafarga Previdi, I., & Vélez Vega, C. M. (2020). Health Disparities Research Framework Adaptation to Reflect Puerto Rico's Socio-Cultural Context. International journal of environmental research and public health, 17(22), 8544.

  13. Santiago, D., Mendoza, A., Morales, Z., & Santos, J. (2020). Characterization of amorphous celecoxib mixed with plasticizing (TPGS) and anti-plasticizing (PVP) ingredients using Hot Melt Extrusion. Journal of pharmaceutical innovation, 15(3), 357–364. PMID: 33343766

  14. Jirau-Colón, H., Toro-Heredia, J., Layuno, J., Calderon, E. D., Gioda, A., & Jiménez-Vélez, B. D. (2021). Distribution of toxic metals and relative toxicity of airborne PM2.5 in Puerto Rico. Environmental science and pollution research international, 1–13. Advance online publication. PMID: 33389579.

  15. Cathey, A. L., Watkins, D. J., Rosario, Z. Y., Vélez Vega, C. M., Loch-Caruso, R., Alshawabkeh, A. N., Cordero, J. F., & Meeker, J. D. (2020). Polycyclic aromatic hydrocarbon exposure results in altered CRH, reproductive, and thyroid hormone concentrations during human pregnancy. The Science of the total environment, 749, 141581. PMID:32829279

  16. Rosa-Casillas, M., Méndez de Jesus, P., Vicente Rodríguez, L. C., Habib, M. R., Croll, R. P., & Miller, M. W. (2020). Identification and Localization of a Gonadotropin Releasing Hormone (GnRH) Related Neuropeptide in Biomphalaria, an Intermediate Host for Schistosomiasis. The Journal of comparative neurology, 10.1002/cne.25099. Advance online publication. PMID: 33368267

  17. Guihurt Santiago, J., Burgos-Tirado, N., Lafontaine, D. D., Mendoza Sierra, J. C., Camacho, R. H., Vecchini Rodríguez, C. M., Morales-Tirado, V., & Flores-Otero, J. (2021). Adhesion G protein-coupled receptor, ELTD1, is a potential therapeutic target for retinoblastoma migration and invasion. BMC cancer, 21(1), 53. PMID: 33430814

  18. Botton, M. R., Whirl-Carrillo, M., Del Tredici, A. L., Sangkuhl, K., Cavallari, L. H., Agúndez, J., Duconge, J., Lee, M., Woodahl, E. L., Claudio-Campos, K., Daly, A. K., Klein, T. E., Pratt, V. M., Scott, S. A., & Gaedigk, A. (2021). PharmVar GeneFocus: CYP2C19. Clinical pharmacology and therapeutics, 109(2), 352–366. PMID: 32602114

  19. Gonzalez-Cordero, A. F., Duconge-Soler, J., Franqui-Rivera, H., Feliu-Maldonado, R., Roche-Lima, A., & Almodovar-Rivera, I. (2021). Insight on the Genetics of Atrial Fibrillation in Puerto Rican Hispanics. Stroke research and treatment, 2021, 8819896. PMID: 33505650.

  20. Campos, M., Pomeroy, J., Mays, M. H., Lopez, A., & Palacios, C. (2020). Intervention to promote physical activation and improve sleep and response feeding in infants for preventing obesity early in life, the baby-act trial: Rationale and design. Contemporary clinical trials, 99, 106185. PMID: 33099015

  21. Rivera-Mariani, F. E., Almaguer, M., Aira, M. J., & Bolaños-Rosero, B. (2020). Comparison of Atmospheric Fungal Spore Concentrations between Two Main Cities in the Caribbean Basin. Puerto Rico health sciences journal, 39(3), 235–242. PMID: 33031690

  22. Cabanillas, F., Morales, J., Conde, J. G., Bertrán-Pasarell, J., Fernández, R., Hernandez-Silva, Y., & Liboy, I. (2021). Home-based management of COVID-19 by identification of low-risk features. medRxiv : the preprint server for health sciences, 2021.01.25.21249684. PMID: 33532797

  23. Ashrap, P., Aker, A., Watkins, D. J., Mukherjee, B., Rosario-Pabón, Z., Vélez-Vega, C. M., Alshawabkeh, A., Cordero, J. F., & Meeker, J. D. (2021). Psychosocial status modifies the effect of maternal blood metal and metalloid concentrations on birth outcomes. Environment international, 149, 106418. PMID: 33548848. PMCID: PMC7897320.

  24. Ralat SI. Using the MMSE-2 to Measure Cognitive Deterioration in a Sample of Psychiatric Patients Living in Puerto Rico. Int J Environ Res Public Health. 2021 Feb 10;18(4):1694. doi: 10.3390/ijerph18041694. PMID: 33578762; PMCID: PMC7916470.

  25. Quiñones-Díaz BI, Reyes-González JM, Sánchez-Guzmán V, Conde-Del Moral I, Valiyeva F, Santiago-Sánchez GS, Vivas-Mejía PE. MicroRNA-18a-5p Suppresses Tumor Growth via Targeting Matrix Metalloproteinase-3 in Cisplatin-Resistant Ovarian Cancer. Front Oncol. 2020 Dec 17;10:602670. doi: 10.3389/fonc.2020.602670. PMID: 33392094; PMCID: PMC7774672.

  26. Crespo NE, Torres-Bracero A, Renta JY, Desnick RJ, Cadilla CL. Expression Profiling Identifies TWIST2 Target Genes in Setleis Syndrome Patient Fibroblast and Lymphoblast Cells. Int J Environ Res Public Health. 2021 Feb 19;18(4):1997. doi: 10.3390/ijerph18041997. PMID: 33669496; PMCID: PMC7922891.

  27. Derilus D, Rahman MZ, Serrano AE, Massey SE. Proteome size reduction in Apicomplexans is linked with loss of DNA repair and host redundant pathways. Infect Genet Evol. 2021 Jan;87:104642. doi: 10.1016/j.meegid.2020.104642. Epub 2020 Dec 6. PMID: 33296723; PMCID: PMC7936648.

  28. Watkins DJ, Torres Zayas HR, Vélez Vega CM, Rosario Z, Welton M, Agosto Arroyo LD, Cardona N, Díaz Reguero ZJ, Santos Rivera A, Huerta-Montañez G, Brown P, Alshawabkeh A, Cordero JF, Meeker JD. Investigating the impact of Hurricane Maria on an ongoing birth cohort in Puerto Rico. Popul Environ. 2020 Sep;42(1):95-111. doi: 10.1007/s11111-020-00345-7. Epub 2020 Mar 17. PMID: 33746324; PMCID: PMC7967016.

  29. Miller MW. Dopamine as a Multifunctional Neurotransmitter in Gastropod Molluscs: An Evolutionary Hypothesis. Biol Bull. 2020 Dec;239(3):189-208. doi: 10.1086/711293. Epub 2020 Nov 20. PMID: 33347799; PMCID: PMC8016498.

  30. Hedges JR, Soliman KFA, Southerland WM, D'Amour G, Fernández-Repollet E, Khan SA, Kumar D, Shikuma CM, Rivers BM, Yates CC, Yanagihara R, Thompson WE, Bond VC, Harris-Hooker S, McClure SA, Ofili EO. Strengthening and Sustaining Inter-Institutional Research Collaborations and Partnerships. Int J Environ Res Public Health. 2021 Mar 8;18(5):2727. doi: 10.3390/ijerph18052727. PMID: 33800316; PMCID: PMC7967451.

  31. Martínez-Matías N, Chorna N, González-Crespo S, Villanueva L, Montes-Rodríguez I, Melendez-Aponte LM, Roche-Lima A, Carrasquillo-Carrión K, Santiago-Cartagena E, Rymond BC, Babu M, Stagljar I, Rodríguez-Medina JR. Toward the discovery of biological functions associated with the mechanosensor Mtl1p of Saccharomyces cerevisiae via integrative multi-OMICs analysis. Sci Rep. 2021 Apr 1;11(1):7411. doi: 10.1038/s41598-021-86671-8. PMID: 33795741; PMCID: PMC8016984.

  32. González-Feliciano JA, Capó-Vélez CM, Akamine P, Delgado-Vélez M, Almodóvar R, Rivera J, Pino I, Morell G, Eichinger D, Rivera JH, Lasalde-Dominicci JA, Baerga-Ortiz A. A reversed phase HPLC method for the quantification of HIV gp145 glycoprotein levels from cell culture supernatants. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Mar 15;1167:122562. doi: 10.1016/j.jchromb.2021.122562. Epub 2021 Jan 27. PMID: 33571843; PMCID: PMC8041096.

  33. Yanagihara R, Berry MJ, Carson MJ, Chang SP, Corliss H, Cox MB, Haddad G, Hohmann C, Kelley ST, Lee ESY, Link BG, Noel RJ Jr, Pickrel J, Porter JT, Quirk GJ, Samuel T, Stiles JK, Sy AU, Taira DA, Trepka MJ, Villalta F, Wiese TE. Building a Diverse Workforce and Thinkforce to Reduce Health Disparities. Int J Environ Res Public Health. 2021 Feb 7;18(4):1569. doi: 10.3390/ijerph18041569. PMID: 33562262; PMCID: PMC7915161.

  34. Malpica-Nieves CJ, Rivera-Aponte DE, Tejeda-Bayron FA, Mayor AM, Phanstiel O, Veh RW, Eaton MJ, Skatchkov SN. The involvement of polyamine uptake and synthesis pathways in the proliferation of neonatal astrocytes. Amino Acids. 2020 Aug;52(8):1169-1180. doi: 10.1007/s00726-020-02881-w. Epub 2020 Aug 20. PMID: 32816168; PMCID: PMC7908810.

  35. Román M, García L, Morales M, Crespo MJ. The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats. Sci Rep. 2021 May 10;11(1):9852. doi: 10.1038/s41598-021-89338-6. PMID: 33972638; PMCID: PMC8110522.

  36. Borrero-García LD, Del Mar Maldonado M, Medina-Velázquez J, Troche-Torres AL, Velazquez L, Grafals-Ruiz N, Dharmawardhane S. Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer. BMC Cancer. 2021 Jun 1;21(1):652. doi: 10.1186/s12885-021-08366-7. PMID: 34074257; PMCID: PMC8170972.

  37. Lewis LM, Mirabelli MC, Beavers SF, Kennedy CM, Shriber J, Stearns D, Morales González JJ, Santiago MS, Félix IM, Ruiz-Serrano K, Dirlikov E, Lozier MJ, Sircar K, Flanders WD, Rivera-García B, Irizarry-Ramos J, Bolaños-Rosero B. Characterizing environmental asthma triggers and healthcare use patterns in Puerto Rico. J Asthma. 2020 Aug;57(8):886-897. doi: 10.1080/02770903.2019.1612907. Epub 2019 Jun 12. PMID: 31187658; PMCID: PMC8225466.

  38. Ríos SC, Colón Sáez JO, Quesada O, Figueroa KQ, Lasalde Dominicci JA. Disruption of the cholinergic anti-inflammatory response by R5-tropic HIV-1 protein gp120JRFL. J Biol Chem. 2021 Mar 31;296:100618. doi: 10.1016/j.jbc.2021.100618. Epub ahead of print. PMID: 33811859; PMCID: PMC8102909.

  39. Rolón-Martínez S, Habib MR, Mansour TA, Díaz-Ríos M, Rosenthal JJC, Zhou XN, Croll RP, Miller MW. FMRF-NH2 -related neuropeptides in Biomphalaria spp., intermediate hosts for schistosomiasis: Precursor organization and immunohistochemical localization. J Comp Neurol. 2021 Sep;529(13):3336-3358. doi: 10.1002/cne.25195. Epub 2021 Jun 11. PMID: 34041754; PMCID: PMC8273141.

  40. Henry Akintobi T, Sheikhattari P, Shaffer E, Evans CL, Braun KL, Sy AU, Mancera B, Campa A, Miller ST, Sarpong D, Holliday R, Jimenez-Chavez J, Khan S, Hinton C, Sellars-Bates K, Ajewole V, Teufel-Shone NI, McMullin J, Suther S, Kimbro KS, Taylor L, Velez Vega CM, Williams C, Perry G, Zuchner S, Marzan Rodriguez M, Tchounwou PB. Community Engagement Practices at Research Centers in U.S. Minority Institutions: Priority Populations and Innovative Approaches to Advancing Health Disparities Research. Int J Environ Res Public Health. 2021 Jun 21;18(12):6675. doi: 10.3390/ijerph18126675. PMID: 34205781; PMCID: PMC8296474.

  41. Ofili EO, Sarpong D, Yanagihara R, Tchounwou PB, Fernández-Repollet E, Malouhi M, Idris MY, Lawson K, Spring NH, Rivers BM. The Research Centers in Minority Institutions (RCMI) Consortium: A Blueprint for Inclusive Excellence. Int J Environ Res Public Health. 2021 Jun 25;18(13):6848. doi: 10.3390/ijerph18136848. PMID: 34202383; PMCID: PMC8296926.