Scientific Publications 2017-2018

Previous Publications


  1. Jang S, Lewis TS, Powers C, Khuchua Z, Baines CP, Wipf P, Javadov S. Elucidating Mitochondrial Electron Transport Chain Supercomplexes in the Heart During Ischemia-Reperfusion. Antioxid Redox Signal. 2017 Jul 1;27(1):57-69. doi: 10.1089/ars.2016.6635. Epub 2016 Nov 11. PubMed PMID: 27604998; PubMed Central PMCID: PMC5488255.

  2. Ballista-Hernández J, Martínez-Ferrer M, Vélez R, Climent C, Sánchez-Vázquez MM, Torres C, Rodríguez-Muñoz A, Ayala- Peña S, Torres-Ramos CA. Mitochondrial DNA Integrity Is Maintained by APE1 in Carcinogen-Induced Colorectal Cancer. Mol Cancer Res. 2017 Jul;15(7):831-841. doi: 10.1158/1541- 7786.MCR-16-0218. Epub 2017 Mar 30. PubMed PMID: 28360037; PubMed Central PMCID: PMC5500394.

  3. Ramos-Benítez MJ, Ruiz-Jiménez C, Aguayo V, Espino AM. Recombinant Fasciola hepatica fatty acid binding protein suppresses toll-like receptor stimulation in response to multiple bacterial ligands. Sci Rep. 2017 Jul 14;7(1):5455. doi: 10.1038/s41598-017-05735-w. PubMed PMID: 28710478; PubMed Central PMCID: PMC5511235.

  4. Martínez-Rivera FJ, Pérez-Laspiur J, Santiago-Gascot ME, Alemán-Reyes AG, García-Santiago E, Rodríguez-Pérez Y, Calo- Guadalupe C, Otero-Pagán I, Ayala-Pagán RN, Martínez M, Cantres-Rosario YM, Meléndez LM, Barreto-Estrada JL. Differential protein expression profile in the hypothalamic GT1-7 cell line after exposure to anabolic androgenic steroids. PLoS One. 2017;12(7):e0180409. doi: 10.1371/journal.pone.0180409. eCollection 2017. PubMed PMID: 28719635; PubMed Central PMCID: PMC5515402.

  5. Cantres-Rosario YM, Acevedo-Mariani FM, Pérez-Laspiur J, Haskins WE, Plaud M, Cantres-Rosario YM, Skolasky R, Méndez- Bermúdez I, Wojna V, Meléndez LM. Microwave & magnetic proteomics of macrophages from patients with HIV-associated cognitive impairment. PLoS One. 2017;12(7):e0181779. doi: 10.1371/journal.pone.0181779. eCollection 2017. PubMed PMID: 28746408; PubMed Central PMCID: PMC5528838.

  6. Encarnación-Medina J, Rodríguez-Cotto RI, Bloom-Oquendo J, Ortiz-Martínez MG, Duconge J, Jiménez-Vélez B. Selective ATP- Binding Cassette Subfamily C Gene Expression and Proinflammatory Mediators Released by BEAS-2B after PM2.5, Budesonide, and Cotreated Exposures. Mediators Inflamm. 2017;2017:6827194. doi: 10.1155/2017/6827194. Epub 2017 Aug 16. PubMed PMID: 28900313; PubMed Central PMCID: PMC5576432.

  7. Salgado-Montilla JL, Rodríguez-Cabán JL, Sánchez-García J, Sánchez-Ortiz R, Irizarry-Ramírez M. Impact of FTO SNPs rs9930506 and rs9939609 in Prostate Cancer Severity in a Cohort of Puerto Rican Men. Arch Cancer Res. 2017;5(3). doi: 10.21767/2254-6081.1000148. Epub 2017 Aug 22. PubMed PMID: 29333375; PubMed Central PMCID: PMC5766011.

  8. Hernandez-Suarez DF, Scott SA, Tomey MI, Melin K, Lopez- Candales A, Buckley CE, Duconge J. Clinical determinants of clopidogrel responsiveness in a heterogeneous cohort of Puerto Rican Hispanics. Ther Adv Cardiovasc Dis. 2017 Sep;11(9):235- 241. doi: 10.1177/1753944717718718. Epub 2017 Jul 4. PubMed PMID: 28675986; PubMed Central PMCID: PMC5555769.

  9. Hampel S, McKellar CE, Simpson JH, Seeds AM. Simultaneous activation of parallel sensory pathways promotes a grooming sequence in Drosophila. Elife. 2017 Sep 9;6. doi: 10.7554/eLife.28804. PubMed PMID: 28887878; PubMed Central PMCID: PMC5614557.

  10. Jang S, Javadov S. Association between ROS production, swelling and the respirasome integrity in cardiac mitochondria. Arch Biochem Biophys. 2017 Sep 15;630:1-8. doi: 10.1016/ Epub 2017 Jul 20. PubMed PMID: 28736227; PubMed Central PMCID: PMC5568452.

  11. Gerena Y, Lozada JG, Collazo BJ, Méndez-Álvarez J, Méndez-Estrada J, De Mello WC. Losartan counteracts the effects of cardiomyocyte swelling on glucose uptake and insulin receptor substrate-1 levels. Peptides. 2017 Oct;96:38-43. doi: 10.1016/j.peptides.2017.09.006. Epub 2017 Sep 7. PubMed PMID: 28889965; PubMed Central PMCID: PMC5618797.

  12. Martínez O, Bravo Cruz A, Santos S, Ramírez M, Miranda E, Shisler J, Otero M. Vaccination with a codon-optimized A27L- containing plasmid decreases virus replication and dissemination after vaccinia virus challenge. Vaccine. 2017 Oct 20;35(44):6007- 6014. doi: 10.1016/j.vaccine.2017.05.091. Epub 2017 Jun 16. PubMed PMID: 28629922; PubMed Central PMCID: PMC5724039.

  13. Ferrer-Acosta Y, Gonzalez-Vega MN, Rivera-Aponte DE, Martinez-Jimenez SM, Martins AH. Monitoring Astrocyte Reactivity and Proliferation in Vitro Under Ischemic-Like Conditions. J Vis Exp. 2017 Oct 21;(128). doi: 10.3791/55108. PubMed PMID: 29155711; PubMed Central PMCID: PMC5755171.

  14. Lozada-Delgado EL, Grafals-Ruiz N, Vivas-Mejía PE. RNA interference for glioblastoma therapy: Innovation ladder from the bench to clinical trials. Life Sci. 2017 Nov 1;188:26-36. doi: 10.1016/j.lfs.2017.08.027. Epub 2017 Aug 31. Review. PubMed PMID: 28864225; PubMed Central PMCID: PMC5617340.

  15. Banna J, Campos M, Gibby C, Graulau RE, Meléndez M, Reyes A, Lee JE, Palacios C. Multi-site trial using short mobile messages (SMS) to improve infant weight in low-income minorities: Development, implementation, lessons learned and future applications. Contemp Clin Trials. 2017 Nov;62:56-60. doi: 10.1016/j.cct.2017.08.011. Epub 2017 Aug 19. PubMed PMID: 28827160; PubMed Central PMCID: PMC5641256.

  16. Nogueras-Ortiz C, Roman-Vendrell C, Mateo-Semidey GE, Liao YH, Kendall DA, Yudowski GA. Retromer stops beta-arrestin 1- mediated signaling from internalized cannabinoid 2 receptors. Mol Biol Cell. 2017 Nov 15;28(24):3554-3561. doi: 10.1091/mbc.E17- 03-0198. Epub 2017 Sep 27. PubMed PMID: 28954865; PubMed Central PMCID: PMC5683765.

  17. Mandalaywala TM, Petrullo LA, Parker KJ, Maestripieri D, Higham JP. Vigilance for threat accounts for inter-individual variation in physiological responses to adversity in rhesus macaques: A cognition × environment approach. Dev Psychobiol. 2017 Dec;59(8):1031-1038. doi: 10.1002/dev.21572. Epub 2017 Oct 25. PubMed PMID: 29071705; PubMed Central PMCID: PMC5690846.

  18. Ortiz AP, Tamayo V, Scorsone A, Soto-Salgado M, Febo I, Piovanetti P, Venegas-Ríos HL, Yamamura Y, Zorrilla C. Prevalence and correlates of cervical HPV infection in a clinic- based sample of HIV-positive Hispanic women. Papillomavirus Res. 2017 Dec;4:39-44. doi: 10.1016/j.pvr.2017.06.006. Epub 2017 Jun 19. PubMed PMID: 29179868; PubMed Central PMCID: PMC5791754.

  19. Rodríguez-Díaz CE, Garriga-López A, Malavé-Rivera SM, Vargas-Molina RL. Zika virus epidemic in Puerto Rico: Health justice too long delayed. Int J Infect Dis. 2017 Dec;65:144-147. doi: 10.1016/j.ijid.2017.07.017. Epub 2017 Nov 15. PubMed PMID: 29153921; PubMed Central PMCID: PMC5725246.

  20. Nuñez RE, Javadov S, Escobales N. Angiotensin II- preconditioning is associated with increased PKC?/PKC? ratio and prosurvival kinases in mitochondria. Clin Exp Pharmacol Physiol. 2017 Dec;44(12):1201-1212. doi: 10.1111/1440- 1681.12816. Epub 2017 Sep 20. PubMed PMID: 28707739; PubMed Central PMCID: PMC6007022.

  21. Anderson J, Seol H, Gordish-Dressman H, Hathout Y, Spurney CF. Interleukin 1 Receptor-Like 1 Protein (ST2) is a Potential Biomarker for Cardiomyopathy in Duchenne Muscular Dystrophy. Pediatr Cardiol. 2017 Dec;38(8):1606-1612. doi: 10.1007/s00246- 017-1703-9. Epub 2017 Aug 18. PubMed PMID: 28821969; PubMed Central PMCID: PMC6317901.

  22. Mansour TA, Habib MR, Rodríguez LCV, Vázquez AH, Alers JM, Ghezzi A, Croll RP, Brown CT, Miller MW. Central nervous system transcriptome of Biomphalaria alexandrina, an intermediate host for schistosomiasis. BMC Res Notes. 2017 Dec 11;10(1):729. doi: 10.1186/s13104-017-3018-6. PubMed PMID: 29228974; PubMed Central PMCID: PMC5725652.

  23. Díaz-Ayala R, Torres-González L, Pietri R, Cabrera CR, López- Garriga J. Engineered (Lys)6-Tagged Recombinant Sulfide- Reactive Hemoglobin I for Covalent Immobilization at Multiwalled Carbon Nanotubes. ACS Omega. 2017 Dec 31;2(12):9021-9032. doi: 10.1021/acsomega.7b01500. Epub 2017 Dec 15. PubMed PMID: 29302632; PubMed Central PMCID: PMC5748273.

  24. Hernandez-Suarez DF, Núñez-Medina H, Scott SA, Lopez- Candales A, Wiley JM, Garcia MJ, Melin K, Nieves-Borrero K, Rodriguez-Ruiz C, Marshall L, Duconge J. Effect of cilostazol on platelet reactivity among patients with peripheral artery disease on clopidogrel therapy. Drug Metab Pers Ther. 2018 Mar 28;33(1):49- 55. doi: 10.1515/dmpt-2017-0032. PubMed PMID: 29408797; PubMed Central PMCID: PMC5840033.

  25. Rodríguez-Díaz CE. Maria in Puerto Rico: Natural Disaster in a Colonial Archipelago. Am J Public Health. 2018 Jan;108(1):30-32. doi: 10.2105/AJPH.2017.304198. PubMed PMID: 29211541; PubMed Central PMCID: PMC5719712.

  26. Colón JM, González PA, Cajigas Á, Maldonado WI, Torrado AI, Santiago JM, Salgado IK, Miranda JD. Continuous tamoxifen delivery improves locomotor recovery 6h after spinal cord injury by neuronal and glial mechanisms in male rats. Exp Neurol. 2018 Jan;299(Pt A):109-121. doi: 10.1016/j.expneurol.2017.10.006. Epub 2017 Oct 13. PubMed PMID: 29037533; PubMed Central PMCID: PMC5723542.

  27. Colón-Cruz L, Kristofco L, Crooke-Rosado J, Acevedo A, Torrado A, Brooks BW, Sosa MA, Behra M. Alterations of larval photo- dependent swimming responses (PDR): New endpoints for rapid and diagnostic screening of aquatic contamination. Ecotoxicol Environ Saf. 2018 Jan;147:670-680. doi: 10.1016/j.ecoenv.2017.09.018. Epub 2017 Sep 19. PubMed PMID: 28934711; PubMed Central PMCID: PMC5681395.

  28. Martínez-Rivera FJ, Barreto-Estrada JL. Reply to: Does High- Frequency Deep Brain Stimulation in Dorsal Regions of the Ventral Striatum Impair Extinction of Morphine-Induced Place Preference?. Biol Psychiatry. 2018 Jan 1;83(1):e21. doi: 10.1016/j.biopsych.2017.06.006. Epub 2017 Jun 10. PubMed PMID: 28673441; PubMed Central PMCID: PMC5880642.

  29. Ferré S, Quiroz C, Guitart X, Rea W, Seyedian A, Moreno E, Casadó-Anguera V, Díaz-Ríos M, Casadó V, Clemens S, Allen RP, Earley CJ, García-Borreguero D. Pivotal Role of Adenosine Neurotransmission in Restless Legs Syndrome. Front Neurosci. 2017;11:722. doi: 10.3389/fnins.2017.00722. eCollection 2017. PubMed PMID: 29358902; PubMed Central PMCID: PMC5766678.

  30. González De León J, González Méndez R, Cadilla CL, Rivera- Mariani FE, Bolaños-Rosero B. Identification of Immunoglobulin E-Binding Proteins of the Xerophilic Fungus Aspergillus penicillioides Crude Mycelial Mat Extract and Serological Reactivity Assessment in Subjects with Different Allergen Reactivity Profiles. Int Arch Allergy Immunol. 2018;175(3):147- 159. doi: 10.1159/000484898. Epub 2018 Feb 3. PubMed PMID: 29402803; PubMed Central PMCID: PMC5847473.

  31. Marqués-Lespier JM, Soto-Salgado M, González-Pons M, Méndez V, Freyre K, Beltrán C, Pericchi LR, Cruz-Correa M. Prevalence of Synchronous Oligopolyposis in Incident Colorectal Cancer: A Population-Based Study. P R Health Sci J. 2018 Mar;37(1):39-45. PubMed PMID: 29547683; PubMed Central PMCID: PMC6116520.

  32. Amaro-Rivera K, López-Cepero A, Diaz B, Lee JE, Palacios C. Micronutrient Intake and the Contribution of Dietary Supplements in Hispanic Infants. J Diet Suppl. 2018 Mar 4;15(2):129-139. doi: 10.1080/19390211.2017.1330300. Epub 2017 Jun 12. PubMed PMID: 28604131; PubMed Central PMCID: PMC5726950.

  33. Ramírez M, Santos S, Martínez O, Rodríguez R, Miranda E, Ramos-Perez WD, Otero M. Characterization of the immune response elicited by the vaccinia virus L3 protein delivered as naked DNA. Vaccine. 2018 Apr 5;36(15):2049-2055. doi: 10.1016/j.vaccine.2018.02.033. Epub 2018 Mar 7. PubMed PMID: 29525282; PubMed Central PMCID: PMC6065253.

  34. Sierra-Mercado D, Lázaro-Muñoz G. Enhance Diversity Among Researchers to Promote Participant Trust in Precision Medicine Research. Am J Bioeth. 2018 Apr;18(4):44-46. doi: 10.1080/15265161.2018.1431323. PubMed PMID: 29621450; PubMed Central PMCID: PMC6053906.

  35. Espinell JRH, López-Mejías V, Stelzer T. Revealing Polymorphic Phase Transformations in Polymer-Based Hot Melt Extrusion Processes. Cryst Growth Des. 2018 Apr 4;18(4):1995-2002. doi: 10.1021/acs.cgd.7b01374. Epub 2018 Mar 9. PubMed PMID: 31889927; PubMed Central PMCID: PMC6936767.

  36. Manfredi B, Morales-Ortíz J, Díaz-Díaz LM, Hernandez-Matias L, Barreto-Vázquez D, Menéndez-Pérez J, Rodríguez-Cordero JA, Villalobos-Santos JC, Santiago-Rivera E, Rivera-Dompenciel A, Lozada-Delgado EL, Kuchibhotla M, Carrasquillo-Carrión K, Roche-Lima A, Washington AV. The Characterization of Monoclonal Antibodies to Mouse TLT-1 Suggests That TLT-1 Plays a Role in Wound Healing. Monoclon Antib Immunodiagn Immunother. 2018 Apr;37(2):78-86. doi: 10.1089/mab.2017.0063. PubMed PMID: 29708866; PubMed Central PMCID: PMC5930940.

  37. Roche-Lima A, Carrasquillo-Carrión K, Gómez-Moreno R, Cruz JM, Velázquez-Morales DM, Rogozin IB, Baerga-Ortiz A. The Presence of Genotoxic and/or Pro-inflammatory Bacterial Genes in Gut Metagenomic Databases and Their Possible Link With Inflammatory Bowel Diseases. Front Genet. 2018;9:116. doi: 10.3389/fgene.2018.00116. eCollection 2018. PubMed PMID: 29692798; PubMed Central PMCID: PMC5902703.

  38. Crespo MJ, Roman M, Matias J, Morales M, Torres H, Quidgley J. Synergistic Effects of Dantrolene and Nimodipine on the Phenylephrine-Induced Contraction and ACh-Induced Relaxation in Aortic Rings from Diabetic Rats. Int J Endocrinol. 2018;2018:9790303. doi: 10.1155/2018/9790303. eCollection 2018. PubMed PMID: 29849627; PubMed Central PMCID: PMC5933070.

  39. Rullán-Lind C, Pietri RB, Vázquez-Cintrón M, Baerga-Ortiz A. Fused dimerization increases expression, solubility, and activity of bacterial dehydratase enzymes. Protein Sci. 2018 May;27(5):969- 975. doi: 10.1002/pro.3404. Epub 2018 Mar 25. PubMed PMID: 29520922; PubMed Central PMCID: PMC5916124.

  40. Reynaldo G, Rodríguez L, Menéndez R, Solazábal J, Amaro D, de Los A Becquer M, Colom Y, Gil H, Polo JC, Castañeda G, Jiménez-Vélez B, Duconge J, Fernández-Sánchez EM. A comparative pharmacokinetic and pharmacodynamic study of two novel Cuban PEGylated rHuEPO versus MIRCERA® and ior®EPOCIM. J Pharm Pharmacogn Res. 2018 May-Jun;6(3):179-190. Epub 2018 Feb 23. PubMed PMID: 30739984; PubMed Central PMCID: PMC6364991.

  41. Hernandez-Suarez DF, Tomassini-Fernandini JC, Cuevas A, Rosario-Berrios AN, Nuñez-Medina HJ, Padilla-Arroyo D, Rivera N, Liriano J, Vega-Roman RK, Renta JY, Melin K, Duconge J. Clinical Relevant Polymorphisms Affecting Clopidogrel Pharmacokinetics and Pharmacodynamics: Insights from the Puerto Rico Newborn Screening Program. Int J Environ Res Public Health. 2018 May 30;15(6). doi: 10.3390/ijerph15061115. PubMed PMID: 29848980; PubMed Central PMCID: PMC6025039.

  42. Fernandez-Repollet E, Locatis C, De Jesus-Monge WE, Maisiak R, Liu WL. Effects of summer internship and follow-up distance mentoring programs on middle and high school student perceptions and interest in health careers. BMC Med Educ. 2018 May 2;18(1):84. doi: 10.1186/s12909-018-1205-3. PubMed PMID: 29716582; PubMed Central PMCID: PMC5930500.

  43. Hernandez-Suarez DF, Botton MR, Scott SA, Tomey MI, Garcia MJ, Wiley J, Villablanca PA, Melin K, Lopez-Candales A, Renta JY, Duconge J. Pharmacogenetic association study on clopidogrel response in Puerto Rican Hispanics with cardiovascular disease: a novel characterization of a Caribbean population. Pharmgenomics Pers Med. 2018;11:95-106. doi: 10.2147/PGPM.S165805. eCollection 2018. PubMed PMID: 29922082; PubMed Central PMCID: PMC5996853.