Publications 2011-2012

Journal Articles

  1. Gerena Y, Gonzalez-Pons M, Serrano AE. Cytofluorometric detection of rodent malaria parasites using red-excited fluorescent dyes. Cytometry A. 2011 Nov;79(11):965-72. doi: 10.1002/cyto.a.21119. PubMed PMID: 22015734; PubMed Central PMCID: PMC3210507. 
     

  2. Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH Jr, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R. Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors. Chem Biol. 2011 Dec 23;18(12):1602- 10. doi: 10.1016/j.chembiol.2011.09.016. PubMed PMID: 22195562; PubMed Central PMCID: PMC3474356. 
     

  3. Valentin II, Vazquez J, Rivera-Miranda G, Seip RL, Velez M, Kocherla M, Bogaard K, Cruz-Gonzalez I, Cadilla CL, Renta JY, Feliu JF, Ramos AS, Alejandro-Cowan Y, Gorowski K, Ruaño G, Duconge J. Prediction of warfarin dose reductions in Puerto Rican patients, based on combinatorial CYP2C9 and VKORC1 genotypes. Ann Pharmacother. 2012 Feb;46(2):208-18. doi: 10.1345/aph.1Q190. PubMed PMID: 22274142; PubMed Central PMCID: PMC3378722. 
     

  4. Acevedo P, Jorge JC, Cruz-Sánchez A, Amy E, Barreto-Estrada JL. A ten-year assessment of anabolic steroid misuse among competitive athletes in Puerto Rico. West Indian Med J. 2011 Oct;60(5):531-5. PubMed PMID: 22519228; PubMed Central PMCID: PMC3436118. 
     

  5. Duconge J, Ruaño G. 'Generic to genetic' transition in cardiovascular and neuropsychiatric drugs: opportunity for personalized medicine. Pharmacogenomics. 2012 Jul;13(10):1097- 100. doi: 10.2217/pgs.12.75. PubMed PMID: 22909196; PubMed Central PMCID: PMC3505752. 
     

  6. Gonzalez MJ, Miranda Massari JR, Duconge J, Riordan NH, Ichim T. Schedule Dependence in Cancer Therapy: Intravenous Vitamin C and the Systemic Saturation Hypothesis. J Orthomol Med. 2012 Jan 1;27(1):9-12. PubMed PMID: 24860238; PubMed Central PMCID: PMC4031610. 
     

  7. Soto-Salgado M, Suárez E, Ortiz AP, Adrovet S, Marrero E, Meléndez M, Colón HM, Albizu C, Del C Santos M, Torres E, Pérez CM. Knowledge of viral hepatitis among Puerto Rican adults: implications for prevention. J Community Health. 2011 Aug;36(4):565-73. doi: 10.1007/s10900-010-9342-6. PubMed PMID: 21125319; PubMed Central PMCID: PMC3463938. Page Continuation Format Page Program Director/Principal Investigator (Last, First, Middle): Publications, 2011-2012, 
     

  8. Boukli NM, Delgado B, Ricaurte M, Espino AM. Fasciola hepatica and Schistosoma mansoni: identification of common proteins by comparative proteomic analysis. J Parasitol. 2011 Oct;97(5):852- 61. doi: 10.1645/GE-2495.1. PubMed PMID: 21506812; PubMed Central PMCID: PMC3564592. 
     

  9. Arocho LC, Figueroa JD, Torrado AI, Santiago JM, Vera AE, Miranda JD. Expression profile and role of EphrinA1 ligand after spinal cord injury. Cell Mol Neurobiol. 2011 Oct;31(7):1057-69. doi: 10.1007/s10571-011-9705-2. PubMed PMID: 21603973; PubMed Central PMCID: PMC3216482. 
     

  10. Morou-Bermudez E, Elias-Boneta A, Billings RJ, Burne RA, Garcia- Rivas V, Brignoni-Nazario V, Suarez-Perez E. Urease activity in dental plaque and saliva of children during a three-year study period and its relationship with other caries risk factors. Arch Oral Biol. 2011 Nov;56(11):1282-9. doi: 10.1016/j.archoralbio.2011.04.015. PubMed PMID: 21616477; PubMed Central PMCID: PMC3182294. 
     

  11. Ortiz AP, Soto-Salgado M, Suárez E, del Carmen Santos-Ortiz M, Tortolero-Luna G, Pérez CM. Sexual behaviors among adults in Puerto Rico: a population-based study. J Sex Med. 2011 Sep;8(9):2439-49. doi: 10.1111/j.1743-6109.2011.02329.x. PubMed PMID: 21676177; PubMed Central PMCID: PMC3474935. 
     

  12. Joshipura KJ, Andriankaja MO, Hu FB, Ritchie CS. Relative utility of 1-h Oral Glucose Tolerance Test as a measure of abnormal glucose homeostasis. Diabetes Res Clin Pract. 2011 Aug;93(2):268-75. doi: 10.1016/j.diabres.2011.05.035. PubMed PMID: 21775009; PubMed Central PMCID: PMC3156353. 
     

  13. García-Crescioni K, Miller MW. Revisiting the reticulum: feedforward and feedback contributions to motor program parameters in the crab cardiac ganglion microcircuit. J Neurophysiol. 2011 Oct;106(4):2065-77. doi: 10.1152/jn.01128.2010. PubMed PMID: 21775716; PubMed Central PMCID: PMC3191840. 
     

  14. Morou-Bermudez E, Elias-Boneta A, Billings RJ, Burne RA, Garcia- Rivas V, Brignoni-Nazario V, Suárez-Pérez E. Urease activity as a risk factor for caries development in children during a three-year study period: a survival analysis approach. Arch Oral Biol. 2011 Dec;56(12):1560-8. doi: 10.1016/j.archoralbio.2011.06.017. PubMed PMID: 21784411; PubMed Central PMCID: PMC3221879. 
     

  15. Franco HL, Casasnovas JJ, Leon RG, Friesel R, Ge Y, Desnick RJ, Cadilla CL. Nonsense mutations of the bHLH transcription factor TWIST2 found in Setleis Syndrome patients cause dysregulation of periostin. Int J Biochem Cell Biol. 2011 Oct;43(10):1523-31. doi: 10.1016/j.biocel.2011.07.003. PubMed PMID: 21801849; PubMed Central PMCID: PMC3163740. Page Continuation Format Page Program Director/Principal Investigator (Last, First, Middle): Publications, 2011-2012, 
     

  16. Ortiz AP, López M, Flores LT, Soto-Salgado M, Finney Rutten LJ, Serrano-Rodriguez RA, Hesse BW, Tortolero-Luna G. Awareness of direct-to-consumer genetic tests and use of genetic tests among Puerto Rican adults, 2009. Prev Chronic Dis. 2011 Sep;8(5):A110. PubMed PMID: 21843413; PubMed Central PMCID: PMC3181183. 
     

  17. Vogel KS, Perez M, Momand JR, Acevedo-Torres K, Hildreth K, Garcia RA, Torres-Ramos CA, Ayala-Torres S, Prihoda TJ, McMahan CA, Walter CA. Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice. Mol Reprod Dev. 2011 Dec;78(12):906-19. doi: 10.1002/mrd.21374. PubMed PMID: 21919107; PubMed Central PMCID: PMC3391697. 
     

  18. Ortiz AP, Thompson CL, Chak A, Berger NA, Li L. Insulin resistance, central obesity, and risk of colorectal adenomas. Cancer. 2012 Apr 1;118(7):1774-81. doi: 10.1002/cncr.26454. PubMed PMID: 22009143; PubMed Central PMCID: PMC3262947. 
     

  19. Castro Mdel R, Suarez E, Kraiselburd E, Isidro A, Paz J, Ferder L, Ayala-Torres S. Aging increases mitochondrial DNA damage and oxidative stress in liver of rhesus monkeys. Exp Gerontol. 2012 Jan;47(1):29-37. doi: 10.1016/j.exger.2011.10.002. PubMed PMID: 22027539; PubMed Central PMCID: PMC3770191. 
     

  20. Miranda-Massari JR, Gonzalez MJ, Jimenez FJ, Allende-Vigo MZ, Duconge J. Metabolic correction in the management of diabetic peripheral neuropathy: improving clinical results beyond symptom control. Curr Clin Pharmacol. 2011 Nov;6(4):260-73. Review. PubMed PMID: 22082324; PubMed Central PMCID: PMC3682498. 
     

  21. Salgado IK, Serrano M, García JO, Martínez NA, Maldonado HM, Báez-Pagán CA, Lasalde-Dominicci JA, Silva WI. SorLA in glia: shared subcellular distribution patterns with caveolin-1. Cell Mol Neurobiol. 2012 Apr;32(3):409-21. doi: 10.1007/s10571-011-9771- 5. PubMed PMID: 22127416; PubMed Central PMCID: PMC3753200. 
     

  22. Rivera-Rivera L, Perez-Laspiur J, Colón K, Meléndez LM. Inhibition of interferon response by cystatin B: implication in HIV replication of macrophage reservoirs. J Neurovirol. 2012 Feb;18(1):20-9. doi: 10.1007/s13365-011-0061-2. PubMed PMID: 22147503; PubMed Central PMCID: PMC3309143. 
     

  23. Palacios C, Gil K, Pérez CM, Joshipura K. Determinants of vitamin D status among overweight and obese Puerto Rican adults. Ann Nutr Metab. 2012;60(1):35-43. doi: 10.1159/000335282. PubMed PMID: 22222318; PubMed Central PMCID: PMC3567879. 
     

  24. Garrett S, Rosenthal JJ. RNA editing underlies temperature adaptation in K+ channels from polar octopuses. Science. 2012 Feb 17;335(6070):848-51. doi: 10.1126/science.1212795. PubMed PMID: 22223739; PubMed Central PMCID: PMC4219319. Page Continuation Format Page Program Director/Principal Investigator (Last, First, Middle): Publications, 2011-2012, 
     

  25. Martínez T, Vazquez GJ, Aquino EE, Goering RV, Robledo IE. Two novel class I integron arrays containing IMP-18 metallo-β-lactamase gene in Pseudomonas aeruginosa clinical isolates from Puerto Rico. Antimicrob Agents Chemother. 2012 Apr;56(4):2119-21. doi: 10.1128/AAC.05758-11. PubMed PMID: 22290962; PubMed Central PMCID: PMC3318352. 
     

  26. De Jesús-Burgos M, Torres-Llenza V, Pérez-Acevedo NL. Activation of amygdalar metabotropic glutamate receptors modulates anxiety, and risk assessment behaviors in ovariectomized estradiol-treated female rats. Pharmacol Biochem Behav. 2012 May;101(3):369-78. doi: 10.1016/j.pbb.2012.01.016. PubMed PMID: 22326382; PubMed Central PMCID: PMC4044914. 
     

  27. Ramos E, Guttierrez-Teissoonniere S, Conde JG, Baez-Cordova JA, Guzman-Villar B, Lopategui-Corsino E, Frontera WR. Anaerobic power and muscle strength in human immunodeficiency virus-positive preadolescents. PM R. 2012 Mar;4(3):171-5. doi: 10.1016/j.pmrj.2011.11.009. PubMed PMID: 22364955; PubMed Central PMCID: PMC3805494. 
     

  28. Palavicini JP, Correa-Rojas RA, Rosenthal JJ. Extra doublestranded RNA binding domain (dsRBD) in a squid RNA editing enzyme confers resistance to high salt environment. J Biol Chem. 2012 May 18;287(21):17754-64. doi: 10.1074/jbc.M112.366005. PubMed PMID: 22457361; PubMed Central PMCID: PMC3366847. 
     

  29. Rosenthal JJ, Seeburg PH. A-to-I RNA editing: effects on proteins key to neural excitability. Neuron. 2012 May 10;74(3):432-9. doi: 10.1016/j.neuron.2012.04.010. Review. PubMed PMID: 22578495; PubMed Central PMCID: PMC3724421. 
     

  30. Rodriguez-Romaguera J, Do Monte FH, Quirk GJ. Deep brain stimulation of the ventral striatum enhances extinction of conditioned fear. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8764-9. doi: 10.1073/pnas.1200782109. PubMed PMID: 22586125; PubMed Central PMCID: PMC3365168. 
     

  31. Parodi-Rullan R, Barreto-Torres G, Ruiz L, Casasnovas J, Javadov S. Direct renin inhibition exerts an anti-hypertrophic effect associated with improved mitochondrial function in post-infarction heart failure in diabetic rats. Cell Physiol Biochem. 2012;29(5- 6):841-50. doi: 10.1159/000178526. PubMed PMID: 22613984; PubMed Central PMCID: PMC3980674. 
     

  32. Gerena Y, Skolasky RL, Velez JM, Toro-Nieves D, Mayo R, Nath A, Wojna V. Soluble and cell-associated insulin receptor dysfunction correlates with severity of HAND in HIV-infected women. PLoS One. 2012;7(5):e37358. doi: 10.1371/journal.pone.0037358. PubMed PMID: 22629383; PubMed Central PMCID: PMC3358319. Page Continuation Format Page Program Director/Principal Investigator (Last, First, Middle): Publications, 2011-2012, 
     

  33. Pagán-Mercado G, Santiago-Cartagena E, Akamine P, Rodríguez- Medina JR. Functional and genetic interactions of TOR in the budding yeast Saccharomyces cerevisiae with myosin type IIdeficiency (myo1Δ). BMC Cell Biol. 2012 May 30;13:13. doi: 10.1186/1471-2121-13-13. PubMed PMID: 22646158; PubMed Central PMCID: PMC3470973. 
     

  34. Rivera-Soto WT, Rodríguez-Figueroa L. Childhood obesity among Puerto Rican children: discrepancies between child's and parent's perception of weight status. Int J Environ Res Public Health. 2012 Apr;9(4):1427-37. doi: 10.3390/ijerph9041427. PubMed PMID: 22690203; PubMed Central PMCID: PMC3366621. 
     

  35. Rodriguez-Franco EJ, Cantres-Rosario YM, Plaud-Valentin M, Romeu R, Rodríguez Y, Skolasky R, Meléndez V, Cadilla CL, Melendez LM. Dysregulation of macrophage-secreted cathepsin B contributes to HIV-1-linked neuronal apoptosis. PLoS One. 2012;7(5):e36571. doi: 10.1371/journal.pone.0036571. PubMed PMID: 22693552; PubMed Central PMCID: PMC3365072. 
     

  36. Ortiz AP, Otero Y, Svensson K, García-Rodríguez O, Garced S, Santiago E, Umpierre S, Figueroa N, Ortiz-Ortiz KJ. Racial and ethnic disparities in lifetime risk of corpus uterine cancer: a comparative study of Puerto Rico and the United States SEER population. Ethn Dis. 2012 Winter;22(1):90-5. PubMed PMID: 22774315; PubMed Central PMCID: PMC4170919. 
     

  37. Castillo-Pichardo L, Dharmawardhane SF. Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer. Nutr Cancer. 2012;64(7):1058-69. doi: 10.1080/01635581.2012.716898. PubMed PMID: 23061908; PubMed Central PMCID: PMC4286176. 
     

  38. De-Regil LM, Palacios C, Ansary A, Kulier R, Peña-Rosas JP. Vitamin D supplementation for women during pregnancy. Cochrane Database Syst Rev. 2012 Feb 15;(2):CD008873. doi: 10.1002/14651858.CD008873.pub2. Review. Update in: Cochrane Database Syst Rev. 2016;(1):CD008873. PubMed PMID: 22336854; PubMed Central PMCID: PMC3747784. 
     

  39. Barreto-Torres G, Parodi-Rullán R, Javadov S. The role of PPARα in metformin-induced attenuation of mitochondrial dysfunction in acute cardiac ischemia/reperfusion in rats. Int J Mol Sci. 2012;13(6):7694-709. doi: 10.3390/ijms13067694. PubMed PMID: 22837722; PubMed Central PMCID: PMC3397554. 
     

  40. Roche-Lima A, Thulasiram RK. Bioinformatics algorithm based on a parallel implementation of a machine learning approach using transducers. J Phys Conf Ser. 2012;341. pii: 012034. PubMed PMID: 27795731; PubMed Central PMCID: PMC5082745. 
     

  41. Montalvo-Ortiz BL, Castillo-Pichardo L, Hernández E, Humphries- Bickley T, De la Mota-Peynado A, Cubano LA, Vlaar CP, Dharmawardhane S. Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase. J Biol Chem. 2012 Apr 13;287(16):13228-38. doi: 10.1074/jbc.M111.334524. PubMed PMID: 22383527; PubMed Central PMCID: PMC3339933. 
     

 

Books (Chapter)

  1. Duconge J, Escalera O, Korchela M, Ruaño G. Clinical Implications fo Genetic Admixture in Hispanic Puerto Ricans: Impacto n the Pharamacogenetics of CYP2C19 and dPON1. D. Sanoudou (ed.) Book Chapter 7; In: Pharmacogenetics, ISBN 978-953-51-0389-9. InTech Open Access Publisher, March 2012 
     
  2. Garcia-Fragoso L, Garcia-Garcia I, and Cadilla CL. The Role of Folic Acid in the Prevention of Neural Tube Defects. In: Neural Tube Defects-Role of Folate, Prevention Strategies and Genetics, ISBN 978-953-51-0317-2, edited by Kannan Laksmi Narasimhan