Dr. Michael Brad Strader, a researcher from National Institutes of Health (NIH) visits the University of Puerto Rico Medical Sciences Campus
Tomography in Electron Microscopy
The RCMI Research Informatics Activity, in collaboration with the Department of Mathematics and Computer Sciences, College of Natural Sciences, University of Puerto Rico at Río Piedras; the SUBE Program, MBRS Program, University of Puerto Rico at Río Piedras; the Resource Center for Sciences and Engineering, EPSCoR, University of Puerto Rico; and the Dean's Office, College of Natural Sciences, University of Puerto Rico at Río Piedras sponsored a seminar on tomography in electron microscopy. The seminar took place on Thursday, March 26, 1998, at the Medical Sciences Campus. The guest speaker, Dr. Gabor T. Herman, talked about the application of algebraic reconstruction techniques (ART) in electron microscopy tomography to recover objects from their projections. Three different modes of data collection were considered: (1) a small set of very noisy images obtained by sequential tilting of a single particle over 120 degrees around a single axis; (2) multiple particles of identical structure placed on a support so that their z-axes are parallel and the support is tilted before taking a single electron micrograph; and (3) a single electron micrograph taken of multiple particles of identical structure placed on the support in random but not equally likely orientations. The advantages of ART were discussed to improve upon the tomographic performance of previously accepted standard techniques.
Dr. Herman is Professor of the Department of Radiology at the University of Pennsylvania. He is currently active in research areas such as image reconstruction, geometry of digital spaces, discrete tomography, and tomographic radiology.
Our special thanks to Dr. Herman for his enlightening presentation.
