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University of Puerto Rico Medical Sciences Campus Receives Dr. Hugh B. Nicholas Jr. from Pittsburgh Supercomputing Center

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Dr. Nicholas

The RCMI AIDS and Emerging Infectious Diseases Program at the UPR-Medical Sciences Campus sponsored the visit of Dr. Hugh B. Nicholas Jr., Senior Scientific Specialist from the Pittsburgh Supercomputing Center on August 19, 2005. Dr. Nicholas presented the seminar Changing substrate specificity by remodeling domain interfaces in glutathione transferases.

In this seminar, he presented an analysis of the major isozyme subfamilies of the cytoplasmic glutathione tranferases that predicts the amino acids responsible for reorienting the glutathione binding domain and the substrate binding domain relative to each other. The cytoplasmic glutathione transferases are medically important in eliminating drugs and chemotherapeutic agents from the body and play an important role in resistance to drugs.

Dr. Nicholas also participated in the oral examination and master’s thesis presentation of Roxana Cintrón Moret, graduate student of Dr. Adelfa E. Serrano. Both activities were well attended, with active participation from faculty members and graduate and undergraduate students.

Contact:
Emma Fernández-Repollet,Ph.D.
Program Director
RCMI Program
Room 621-A, 6th. floor
Main Building, Medical Sciences Campus
GPO Box 365067
San Juan, PR 00936-5067
Email: e.fernandez@upr.edu
Telephones:
Voice (787) 763-9401
FAX (787) 758-5206

 

 

The project is supported by Grant Number G12RR03051(RCMI Program, University of Puerto Rico Medical Sciences Campus) from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH). Its contents are solely the responsibility of the authors and do not necessarily represent the official views of NCRR or NIH.